Drug-pricing rules embedded in the Inflation Reduction Act will trigger the most significant changes in nearly two decades to the way the government pays for prescription drugs, including caps on patient spending and drugmaker price increases.

Legislation that the House of Representatives passed Friday would raise an estimated $739 billion in revenue and spend $433 billion on climate and energy programs as well as health-insurance subsidies for millions of people covered under the Affordable Care Act. President Biden is expected to sign the bill soon.

This post first appeared on wsj.com

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