After months of mounting distrust in potential coronavirus vaccines, Americans’ confidence in preventive shots is on the rise at last. 

As of a Gallup survey taken between October 19 and November 1, 58 percent of Americans said they would take a vaccine to prevent COVID-19. 

Responses were submitted just weeks before Pfizer announced that its vaccine is 90 percent effective at preventing coronavirus infection and Moderna subsequently revealed its shot is 94.5 percent effective. 

Public health experts have been deeply concerned for months that, even if a COVID-19 vaccine proved safe and effective in testing, it would do little good if too few people were willing to take it. 

But despite worries that President Trump’s push vaccine approval to be rushed ahead of the election, vaccine-makers took their time to continue studies, and the tide of Americans’ trust in them began to turn even before data on the shots was released. 

Confidence in a coronavirus vaccine fell for months, with the country split on whether or not to get one in September. As of late October/early November - before Pfizer and Moderna announced their data - 58% of Americans would get an FDA-approved shot

Confidence in a coronavirus vaccine fell for months, with the country split on whether or not to get one in September. As of late October/early November - before Pfizer and Moderna announced their data - 58% of Americans would get an FDA-approved shot

Confidence in a coronavirus vaccine fell for months, with the country split on whether or not to get one in September. As of late October/early November – before Pfizer and Moderna announced their data – 58% of Americans would get an FDA-approved shot 

By the time the latest survey was administered to 2,985 Americans over 18, U.S. coronavirus cases had begun to tick up. 

During the week ending in October 25, there were 481,372 new coronavirus cases. 

That marked a 23 percent increased over the previous week’s 392,048 new cases. 

Meanwhile, confidence in a prospective COVID-19 vaccine improved. 

When Gallup took its previous survey, between September and 27 (during which two-week period 606,780 new cases were diagnosed) Americans were split 50/50 on whether or not they wanted to get vaccinated against COVID-19. 

The shift in opinion was far from uniform across demographics, however.

Among Republicans, the percentage of people willing to get vaccinated when asked in October/November was exactly the same as the share who said they would get a COVID-19 shot in September: 49 percent. 

The share of Independents who would get vaccinated rose slightly, from 47 percent to 49 percent. 

Confidence in a vaccine among Democrats (blue) shot up from 53% to 69% in a month, while Republicans' willingness to get vaccinated (red) remained stable at 49%

Confidence in a vaccine among Democrats (blue) shot up from 53% to 69% in a month, while Republicans' willingness to get vaccinated (red) remained stable at 49%

Confidence in a vaccine among Democrats (blue) shot up from 53% to 69% in a month, while Republicans’ willingness to get vaccinated (red) remained stable at 49% 

Willingness to get vaccinated shot up among Democrats in late October and November after steeply declining from August to September.

As of the most recent round of polling, 69 percent of Democrats are willing to get a coronavirus, inching back toward summer confidence levels between 78 and 83 percent among liberals. 

Women are currently less willing to take a COVID-19 vaccine, compared to men, but the portion who plan to get a shot had grown more dramatically since September. 

In the previous survey, just 44 percent of women and 56 percent of men planned to get vaccinated. 

By the time of the October/November survey, 61 percent of men said they would get a COVID-19 that was approved by the Food and Drug Administration (FDA) if one was available that day. 

The most common reason people were unwilling to get vaccinated was still concern that shots have been rushed

The most common reason people were unwilling to get vaccinated was still concern that shots have been rushed

The most common reason people were unwilling to get vaccinated was still concern that shots have been rushed 

Confidence increased among all age, racial and regional groups, as well as among people with any level of education. 

Gallup also asked Americans about what fueled their worries over coronavirus vaccines. 

The most common concern, shared by 37 percent of those surveyed, was still the rushed timeline, even after changes to FDA guidelines made it effectively impossible for a vaccine to be ready for approval before Election Day. 

For another 26 percent who wanted to wait to ese if a vaccine was safe and another 10 percent who wanted to see if it was effective, their questions may now be answered, with the revelations that Pfizer and partner BioNTech’s vaccine is 90 percent effective, and Moderna’s is 94.5 percent effective.

Neither vaccine-maker has reported major safety concerns associated with their shots, though some trial participants have described the side effects as like having a terrible flu or even a hangover.

Perhaps most worrying, 12 percent of the survey respondents said they don’t trust vaccines in general – which could signal that a substantially section of the U.S. population is hesitant to get a vaccine that could protect against COVID-19 or against other currently controlled diseases, like measles. 

US government’s plan to effectively distribute the jab to Americans once it’s available: How will it work? 

Who will get the vaccine first and when will it be rolled out?

HHS secretary Alex Azar has offered up a timeline regarding who would be the first to receive the COVID-19 vaccination if they can start rolling out the jabs next month as planned. 

The elderly in nursing homes and assisted living facilities will likely be the first to the vaccinated.  

Adults with underlying medical conditions that put them at risk of severe COVID-19 illness and people over 65 years of age could also fall into this initial category, according to  according to Operation Warp Speed’s strategy plan.  

Inoculations of healthcare workers and first responders will follow, with a goal to complete those shots by the end of January. 

Azar said he expects to have enough vaccinations for ‘all Americans’ by the end of March to early April. 

Dr Anthony Fauci agreed with this determination, predicting that Americans will likely be vaccinated by April.  

A final priority list is still being determined by the CDC’s Advisory Committee on Immunization Practices that will based, in part, on vaccine efficacy data from the various trials, including Pfizer and Moderna.

This chart shows Operation Warp Speed's distribution plan from when a vaccine is approved by the FDA to being given to administration sites

This chart shows Operation Warp Speed's distribution plan from when a vaccine is approved by the FDA to being given to administration sites

This chart shows Operation Warp Speed’s distribution plan from when a vaccine is approved by the FDA to being given to administration sites

How many shots will you have to get and how much will it cost? 

The COVID-19 vaccine will need to be taken in two doses about three weeks apart to be fully effective.

While there could be multiple vaccines available by next year, they are not interchangeable if they have been developed by different companies. 

This means the second dose needs to be from the same manufacturer as the first dose.  

Operation Warp Speed’s strategy plan details that those providing the vaccine should be giving out vaccine record cards that details the manufacturer. Record cards can also serve as a reminder about getting the second dose.

Congress and President Donald Trump have already enacted legislation that calls for the vaccines to be free to all Americans. 

How many will the US have available? 

The government already has a $1.95 billion contract for 100 million doses of the Pfizer vaccine, which is enough to inoculate 50 million people, with an option to acquire 500 million more. 

The government will also secure 100 million doses of Moderna’s vaccine after paying $1.5 billion, with an option for another 400 million doses.   

Pfizer has already said it will distribute its own vaccine from its facilities straight to administration sites. Other vaccines will be shipped by a government contractor from the manufacturer

Pfizer has already said it will distribute its own vaccine from its facilities straight to administration sites. Other vaccines will be shipped by a government contractor from the manufacturer

Pfizer has already said it will distribute its own vaccine from its facilities straight to administration sites. Other vaccines will be shipped by a government contractor from the manufacturer

Where will Americans be able to get COVID-19 vaccinations?

The government will be allocating vaccine supplies to states which will then be responsible for administering the jabs. 

The government is organizing a free distribution of the vaccine to US states and territories, with each jurisdiction to decide how to distribute the doses to hospitals, pharmacies, doctors or even universities.  

In the early stages of the roll out, the CDC has recommended that states make vaccines available at large hospitals and health systems, pharmacies, mobile vaccination providers, occupational health settings for large employers, critical access hospitals, rural health clinics, community health centers and other central locations that can provide vaccination services for a broad area.

The CDC says it has existing agreements with CVS and Walgreens to assist with on-site vaccinations at long-term care facilities.  

Operation Warp Speed has indicated they want vaccinations to be available at all healthcare professionals who are licensed to administer vaccines, including pharmacies. 

The pharmacies that have already signed on to provide vaccinations, according to the CDC, include: Walgreens, CVS, Walmart, Rite Aid, Kroger Co., Albertsons and Costco.  

Who is in charge of shipping out the vaccinations and how will they be handled?

While US Army general Gus Perna is coordinating the distribution of the vaccine, the military will not be involved in shipping out the vaccine to the locations where the jabs will be administered. 

Vaccines made by Moderna and other candidates will be shipped directly from the manufacturer by medical supply company McKesson Corp.  

McKesson, who has been contracted by Operation Warp Speed for distribution, was also contracted by the government to distribute H1N1 vaccines during that pandemic in 2009-2010.   

Pfizer has already said it will distribute its own vaccine from its facilities in Kalamazoo, Michigan and Pleasant Prairie, Wisconsin.

The drugmaker has already created a staging ground at its Michigan facility complete with 350 large freezers to hold the vaccines once they’re created and ready to ship. 

Pfizer’s ship-out will include a precise, clockwork-like dance of containers, trucks and planes.

The vaccine needs to be stored at -94 degrees Fahrenheit, so thermal shipping containers will each be filled with dry ice and 975 vials of the vaccine which each contain five doses, for a total of 4,875 doses.

Every day six trucks will take the doses to air carriers such as FedEx, UPS or DHL, which will deliver them across the US in one to two days and across the globe in three. The company expects an average of 20 daily cargo flights worldwide. 

FedEx had to obtain special permission from civil aviation authorities to transport so much dry ice, which could pose a danger to the crew should it accidentally undergo ‘sublimation’ and pass from a solid to a gas, the company 

Once the boxes have reached their final destination, they can be opened only briefly just two times a day. The vaccines can remain in their boxes for two weeks meaning hospitals will not need a special freezer. 

Moderna’s vaccine can be stored at -4 degrees Fahrenheit, which is the temperature of a normal freezer.

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This post first appeared on Dailymail.co.uk

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