Amid claims PM wanted to be infected with Covid on TV, volunteers tell of taking part in a human challenge trial

If Dominic Cummings is to be believed, Boris Johnson was so sceptical that Covid-19 was a threat early last year that he was willing to inject himself with the virus that causes the disease on television. But there are actual volunteers – young and healthy people – who elected to be infected with the virus, all in the name of science.

These volunteers lined up to participate in “human challenge trials”, which have long been successfully employed to develop vaccines for diseases from typhoid to cholera.

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