At best, vaccines and lockdown could make life more normal by May. But at worst, a new mutation could undo any progress

Hopes are rising that Britain may soon put the worst of Covid-19 behind it. After a year in which the disease has paralysed the nation, killed more than 100,000 people, closed schools and universities, and brought the NHS to its knees, there are now signs of hope emerging.

Most optimism stems from Britain’s vaccination programme, which has resulted in the inoculation of more than 10 million people in the past two months alone, and which aims to have vaccinated the entire adult population later this year.

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